Thyatira (or Thyateira) was about 42
miles from the Aegean Sea, in the valley of the Lycus River, a branch of
the Hermus. It stood at the junction of three main roads leading to
Pergamum (37 miles northwest), Sardis (37 miles southeast) and Smyrna
(47 miles southeast). Originally it was an insignificant town founded by
Lydians from Sardis who called it Pelopia. At the beginning of the 3rd
century BC it was re-founded by Seleucus I Nicator (311-280 BC) as a
military outpost to guard the vulnerable southeast approach to Pergamum.
He named it Thyatira after being informed of the birth of his daughter
(Greek thygater) and settled it with soldiers from Macedonia.
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